SUMOylation of Fragile X Mental Retardation Protein: A Critical Mechanism of FMRP-Mediated Neuronal Function

作     者：Mingzhu Tang Liqun Lu Feng Xie Linxi Chen 

作者机构：Institute of Pharmacy and Pharmacology Learning Key Laboratory for Pharmacoproteomics Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study University of South China 

出 版 物：《Neuroscience Bulletin》 (神经科学通报（英文版）)

年 卷 期：2018年第34卷第6期

页      面：1100-1102页

核心收录：

学科分类：10[医学] 

基　　金：supported by the National Natural Science Foundation of China (81503074) 

主　　题：FXS AD In SUMOylation of Fragile X Mental Retardation Protein 

摘      要：Recently, Khayachi et al.;showed that fragile X mental retardation protein （FMRP） is an active substrate of the small ubiquitin-like modifier （SUMO） pathway in *** SUMOylation is induced by the activation of metabotropic glutamate receptors （mGlu5Rs）. FMRP