Steroidal saponins from the roots of Asparagus cochinchinensis

作     者：ZHU Guo-Lei HAO Qian LI Rong-Tao LI Hai-Zhou 

作者机构：Faculty of Life Science and TechnologyKunming University of Science and Technology 

出 版 物：《Chinese Journal of Natural Medicines》 (中国天然药物（英文版）)

年 卷 期：2014年第12卷第3期

页      面：213-217页

核心收录：

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

基　　金：supported by the National Natural Science foundation of China(No.20962013) 

主　　题：Asparagus cochinchinensis Asparagaceae Steroidal saponins 

摘      要：AIM： To study the chemical constituents of the roots of Asparagus cochinchinensis （Asparagaceae）. METHOD： The compounds were isolated with Diaion HP20, silica gel, and ODS chromatography, and their structures were de- termined on the basis of chemical methods, HR-ESI-MS, and 1 D- and 2D-NMR techniques. RESULTS： Seven compounds were isolated from the n-butanol fraction of the roots of A. cochinchinensis, and their structures were elucidated as （25S）-26-O-β-D-glucopyranosyl-5β-furostan-3β, 22a, 26-triol-12-one-3-O-β-D-glucopyranoside （1）, （25S）-26- O-β-D-glucopyranosyl-22a-methoxy-5β-furostan-3p, 26-diol-12-one-3-O-β-D-glucopyranoside （2）, （25S）-26-O-β-D-glucopyra- nosyl-5β-furostan-3β, 22a, 26-triol （3）, （25S）-26-O-β-D-glucopyranosyl-5β-furstan-3β, 22a, 26-triol-3-O-β-D-glucopyranoside （4）, （25S）-26-O-β-D-glucopyranosyl-5β-furostan-3β, 22a, 26-triol-3-O-a-L-rhamnopyranosyl-（1, 4）-β-D-glucopyranoside （5）, （25S）- 5β-spirostan-3fl-ol-3-O-a-L-rhamnopyranoside （6）, and （25S）-5β-spirostan-3β-ol-3-O-β-D-glucopyranoside （7）. CONCLUSION： Compounds 1 and 2 were two new furostanol saponins.