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From Droplets and Particles to Hierarchical Spatial Organization: Nanotechnology Challenges for Microfluidics

From Droplets and Particles to Hierarchical Spatial Organization: Nanotechnology Challenges for Microfluidics

作     者:J. Michael Kohler P. Mike Gvnther Anette Funfak Jialan Cao Andrea Knauer Shuning Li Steffen Schneider G. Alexander Gross 

作者机构:Techn. Univ. llmenau Institute of Micro- and Nanotechnologies/Institute for Physics Dept. Phys. Chem. and MicroreactionTechnology llmenau Germany 

出 版 物:《Journal of Physical Science and Application》 (物理科学与应用(英文版))

年 卷 期:2011年第1卷第3期

页      面:125-134页

学科分类:1205[管理学-图书情报与档案管理] 12[管理学] 120501[管理学-图书馆学] 120502[管理学-情报学] 

主  题:Nanotechnology microfluidics nanoparticles segmented flow concentration spaces screening nested phases hierarchical organization droplet-based systems. 

摘      要:The compartimentation of fluids in the microliter, nanoliter and picoliter range leads recently to many applications of microfluidics in material development, diagnostics and biological screenings. Droplet-based microfluidics allows the improvement of nanoparticle homogeneity and the tuning of particle properties. It supports combinatorial synthesis of inorganic as well as organic substances and can be applied for the cultivation and screening of bacteria, eucaryotic cells and fish embryos. The well-ordered handling and the addressing of microfluid segments improves the information transfer between chemical, biological and electronic systems. Despite this remarkable technical progress, there is a particular importance of microfluidics for future nanotechnological solutions. The hierarchical spatial organization of liquids, particles and gels in microfluidics represents a fundamental biomimetic principle which overcomes the limits of planar technology and opens the gate for realizing complex structured threedimensional nanoarchitectures. Recent applications of microstructured fluids in chemistry and biology and concepts for future developments will be discussed.

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