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Risk factors of electrocoagulation syndrome after esophageal endoscopic submucosal dissection

Risk factors of electrocoagulation syndrome after esophageal endoscopic submucosal dissection

作     者:Dae Won Ma Young Hoon Youn Da Hyun Jung Jae Jun Park Jie-Hyun Kim Hyojin Park 

作者机构:Department of Internal Medicine Gangnam Severance Hospital Yonsei University College of Medicine 

出 版 物:《World Journal of Gastroenterology》 (世界胃肠病学杂志(英文版))

年 卷 期:2018年第24卷第10期

页      面:1144-1151页

核心收录:

学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基  金:Supported by Basic Science Research Program through the National Research Foundation of Korea(NRF) funded by the Ministry of Science and ICT No.NRF-2015R1C1A1A01054352 

主  题:Electrocoagulation Endoscopic submucosal dissection Esophageal neoplasm Syndrome 

摘      要:AIM To investigate post endoscopic submucosal dissection electrocoagulation syndrome(PEECS) of the *** We analyzed 55 consecutive cases with esophageal endoscopic submucosal dissection for superficial esophageal squamous neoplasms at a tertiary referral hospital in South Korea. Esophageal PEECS was defined as mild meeting one of the following criteria without any obvious perforation: fever(≥ 37.8 ℃), leukocytosis( 10800 cells/μl), or regional chest pain more than 5/10 points as rated on a numeric pain intensity scale. The grade of PEECS was determined as severe when meet two or more of above *** We included 51 cases without obvious complications in the analysis. The incidence of mild and severe esophageal PEECS was 47.1% and 17.6%, respectively. Risk factor analysis revealed that resected area, procedure time, and muscle layer exposure were significantly associated with PEECS. In multivariate analysis, a resected area larger than 6.0 cm^2(OR = 4.995, 95%CI: 1.110-22.489, P = 0.036) and muscle layer exposure(OR = 5.661, 95%CI: 1.422-22.534, P = 0.014) were independent predictors of esophageal PEECS. All patients with PEECS had favorable outcomes with conservative management approaches, such as intravenous hydration or *** Clinicians should consider the possibility of esophageal PEECS when the resected area exceeds 6.0 cm^2 or when the muscle layer exposure is noted.

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