Sequential spinal and intracranial dural metastases in gastric adenocarcinoma: A case report

作     者：Hongsik Kim Kyung Sik Yi Won-Dong Kim Seung-Myoung Son Yaewon Yang Jihyun Kwon Hye Sook Han 

作者机构：Department of Internal Medicine Chungbuk National University Hospital Department of Radiology Chungbuk National University Hospital Department of Radiation Oncology College of Medicine Chungbuk National University Department of Radiation Oncology Chungbuk National University Hospital Department of Pathology Chungbuk National University Hospital Department of Internal Medicine College of Medicine Chungbuk National University 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2018年第24卷第5期

页      面：651-656页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Adenocarcinoma Gastric Metastasis Dura Radiotherapy 

摘      要：Dural metastasis from primary gastric adenocarcinoma has been rarely reported, and its prognosis is very poor because it frequently leads to acute subdural hematoma. Here, we describe a case with sequential spinal and cranial dural metastases from gastric adenocarcinoma without subdural hematoma. A 43-yearold woman with gastric adenocarcinoma and wellcontrolled peritoneal carcinomatosis presented with back pain, right radiating leg pain, left facial palsy, and hearing loss. Magnetic resonance imaging of the spine and brain revealed dural masses at the lumbosacral junction with invasion to the L5 and S1 nerve roots and at the skull base with invasion to the internal auditory canal. She was treated with local radiotherapy, and her pain and neurologic symptoms improved after palliative radiotherapy. This is the first reported case of dural metastases of gastric adenocarcinoma of the spine and skull base but with a relatively indolent course and without subdural hematoma.