Aqueous Knoevenagel Condensation Catalyzed by Aminopropyl-functionalized MCM-41

作     者：Guo Hua GAO Jin Bao GAO Wen Juan ZHOU Liang LU Ming Yuan HE 

作者机构：Shanghai Key Laboratory of Green Chemistry and Chemical Process Department of Chemistry East China Normal University Shanghai 200062 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2006年第17卷第10期

页      面：1293-1296页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 070304[理学-物理化学(含∶化学物理)] 08[工学] 0817[工学-化学工程与技术] 0703[理学-化学] 

基　　金：SRF for ROCS  SEM and Science and Technology Commission of Shanghai Municipality 

主　　题：Knoevenagel condensation aqueous-phase reaction aminopropyl-functionalized MCM41. 

摘      要：An efficient, environmentally friendly procedure is developed for the condensation of aldchydcs/kctoncs and activated methylene compounds by using an aminopropyl-functionalized MCM-41 catalyst in aqueous solution. Different aldchydcs/kctoncs and activated methylene compounds gave the corresponding alkcncs in 78-97% isolated yields in mild reaction conditions. In comparison with organic solution, the aqueous solution gives higher yields in the same reaction conditions. Further more, the aminopropyl-functionalizcd MCM-41 in aqueous system can be reused for 8 flints without significant decrease of activity.