Wnt5a Affects Schwann Cell Proliferation and Regeneration via Wnt/c-Jun and PTEN Signaling Pathway

作     者：Fei Yu Jian Weng Yu-Song Yuan Yu-Hui Kou Na Han Bao-Guo Jiang Pei-Xun Zhang 

作者机构：Department of Orthopedics and Trauma Peking University People's Hospital Beijing 100044 China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2018年第131卷第21期

页      面：2623-2625页

核心收录：

学科分类：040106[教育学-高等教育学] 0710[理学-生物学] 0401[教育学-教育学] 04[教育学] 07[理学] 08[工学] 09[农学] 071007[理学-遗传学] 0901[农学-作物学] 0836[工学-生物工程] 090102[农学-作物遗传育种] 

基　　金：continuously funded by grants from the National Natural Science Foundation of China Innovation Team of the Ministry of Education 

摘      要：To the Editor： Peripheral nerve injury has been a common clinical disease, and delayed treatment may ultimately lead to long-term physical dysfunction. The repair of peripheral nerve injury has become a major challenge in clinical practice. Different from the central nervous system, the peripheral nervous system has the capacity to regenerate after injury. However, the peripheral nerve regeneration after injury is a slow process, and more than 3 months is usually needed for the axons regenerating to the distal target organs or tissues, when the distal nerve stump and skeletal muscle usually become atrophy and the regenerated axons lost the ability to remodel in next few months.