Significance of continuous rotavirus and norovirus surveillance in Indonesia

作     者：Mohamad Saifudin Hakim Hera Nirwati Abu Tholib Aman Yati Soenarto Qiuwei Pan 

作者机构：Department of Gastroenterology and HepatologyErasmusMC-University Medical Center and Postgraduate SchoolMolecular MedicineRoom Na-1001's-Gravendijkwal2303015CE RotterdamThe Netherlands Department of Micr obiologyFaculty of MedicineUniversitas Gadjah MadaYogyakartaIndonesia Department of Child HealthFaculty of MedicineUniversitas Gadjah MadaYogyakartaIndonesia 

出 版 物：《World Journal of Pediatrics》 (世界儿科杂志（英文版）)

年 卷 期：2018年第14卷第1期

页      面：4-12页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：The Indonesia Endowment Fund for Education (LPDP) 

主　　题：Diarrhea Rotavirus Norovirus Indonesia Surveillance 

摘      要：Background Diarrhea significantly contributes to the global burden of diseases, particularly in developing countries. Rota-virus and norovirus are the most dominant viral agents responsible for diarrheal disease globally. The aim of this review was to conduct a comprehensive assessment of rotavirus and norovirus study in Indonesia. Data sources Articles about rotavirus and norovirus surveillance in Indonesia were collected from databases, including PubMed and Google Scholar. Manual searching was performed to identify additional studies. Furthermore, relevant articles about norovirus diseases were included. Results A national surveillance of rotavirus-associated gastroenteritis has been conducted for years, resulting in substantial evidence about the high burden of the diseases in Indonesia. In contrast, norovirus infection received relatively lower attention and very limited data are available about the incidence and circulating genotypes. Norovirus causes sporadic and epidemic gastroenteritis globally. It is also emerging as a health problem in immunocompromised individuals. During post-rotavirus vaccination era, norovirus potentially emerges as the most frequent cause of diarrheal diseases. Conclusions Our review identifies knowledge gaps in Indonesia about the burden of norovirus diseases and the circulating genotypes. Therefore, there is a pressing need to conduct national surveillance to raise awareness of the community and national health authority about the actual burden of norovirus disease in Indonesia. Continuing rotavirus surveillance is also important to assess vaccine effectiveness and to continue tracking any substantial changes of circulating rotavirus genotypes.