多灶性脉络膜炎及全葡萄膜炎患者的长期随访观察

作     者：Vianna R.N.G. Ozdal P.C. Filho J.P.S. 程燕 

作者机构：Avenue Ary Pa rreiras 438 Niteroi Rio de Janeiro 2423-322 Brazil Dr. 

出 版 物：《世界核心医学期刊文摘（眼科学分册）》 (Digest of the World Core Medical Journals:Ophthalmology)

年 卷 期：2005年第1卷第5期

页      面：17-17页

学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学] 

主　　题：葡萄膜炎 脉络膜炎 多灶性 脉络膜新生血管 黄斑囊样水肿 黄斑病变 白内障手术 眼部并发症 生存分析 后囊 

摘      要：Purpose: To report the visual prognosis and longterm complications in patients with multifocal choroiditis and panuveitis (MCP). Methods: A retrospective stud y was performed with patients who met inclusion criteria for MCP at the Uveitis Clinic, Royal Victoria Hospital, McGill University, Montreal, Canada. Informatio n collected included duration of follow-up, visual acuity (VA) measured at each clinical visit, ocular and systemic treatment and ocular complications observed during follow-up. Results: Nineteen patients (37 eyes) with MCP with a mean fo llow-up of 76.9 months were studied. Kaplan-Meier survival analysis showed a d ecrease in the proportion of patients with a final VA ≥20/40 over time. Cystoid macular oedema was seen in 29.7%of the eyes and was the most frequent macular abnormality observed in our group. On the other hand, choroidal neovascularizati on was detected in only six (16.2%) of the eyes, but was related to VA 20/200 in four of these eyes. Glaucoma was detected in 10.8%of the eyes. Cataract (po sterior subcapsular and/or nuclear) was the most common longterm complication, o ccurring in 40%of affected eyes. Cataract surgery improved the VA in 83.3%of t hese eyes. Conclusion: The visual acuity of patients with MCP decreases with tim e. Visual loss can occur from complications following the inflammation itself an d/or iatrogenic induced by the chronic use of corticosteroids.