Microwave-assisted chemoselective copper-catalyzed amination of o-chloro and o-bromobenzoic acids using aromatic amines under solvent free conditions

作     者：Yaghoub Sarrafi Manijeh Mohadeszadeh Kamal Alimohammadi 

作者机构：Faculty of ChemistryMazandaran UniversityBabolsarIran 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2009年第20卷第7期

页      面：784-788页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：the financial support of this work by the Research Council of Mazandaran University 

主　　题：Microwave-assisted Copper-catalyzed Solvent free Amination N-Aryl anthranilic acid 

摘      要：Copper-catalyzed synthesis of N-aryl anthranilic acid derivatives using effective amination of 2-chloro and 2-bromobenzoic acid under microwave irradiation is reported. Some of the advantages of this method are high chemoselectivity, short reaction times, ease of work up procedure and elimination of the need for acid protection. 2009 Published by Elsevier B.V. on behalf of Chinese Chemical Society.