Clinical and impression cytology findings of amniotic membrane and oral mucosal membrane transplantation for the management of socket contracture
Clinical and impression cytology findings of amniotic membrane and oral mucosal membrane transplantation for the management of socket contracture作者机构：Department of Ophthalmology Hacettepe University
出 版 物：《International Journal of Ophthalmology(English edition)》 (国际眼科杂志（英文版）)
年 卷 期：2014年第7卷第2期
页 面：340-344页
核心收录：
学科分类：1003[医学-口腔医学] 100302[医学-口腔临床医学] 10[医学]
主 题：socket reconstruction amniotic membrane oral mucosal membrane
摘 要：AIM:To investigate and compare the cytopathological and clinical effects of amniotic membrane transplantation(AMT)and oral mucosal membrane transplantation(OMMT)in socket ***:Twelve patients who could not be fitted with ocular prosthesis due to socket contracture were included in this *** patients underwent AMT and 5 patients underwent *** patients who had healthy sockets were included as control *** of inferior fornix,degree of inflammation,extent of the socket contracture and socket volume were measured in the preoperative period and at sixth and twelfth weeks *** cytology of conjunctival fornices and tear transforming growth factor beta-1(TGFβ1)levels were ***:In the AMT group,socket volume and lower fornix depth values were significantly higher(P=0.030and P=0.004 respectively)and inflammation levels and impression cytology stages(P=0.037 and P=0.022respectively)were significantly lower in postoperative period compared to preoperative *** the OMMT group,no statistical differences were found in terms of clinical parameters,inflammation levels and impression cytology stages of preoperative versus postoperative *** tear TGFβ1 levels were higher in AMT and OMMT groups compared to the control group(25.5 ng/mL,26.3 ng/mL and 21.7 ng/mL respectively).Decreased tear TGFβ1 levels were observed in both the AMT and OMMT groups postoperatively(median decrease value=2.1 ng/mL and 2.7 ng/mL respectively).CONCLUSION:AMT is associated with postoperative improvement in inferior fornix depth,socket volume,inflammation and impression cytology levels and may bea more proper alternative method than OMMT in the management of socket contracture.
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