The Total Synthesis of (±)-Hinesol and (±)-Agarospirol

作     者：Jin Jun WANG Chang Jin YUE Jun QIU (Department Of Fine Chemistry, Jilin Chemical Engineering College, Jilin, 132002)Cang Yi QIAN(Department of Chemistry, Qing Hua University, Beijing, 100084) 

作者机构：Department of Fine Chemistry Jilin Chemical Engineering College Jilin 132002 China Department of Chemistry Qing Hua University Beijing 100084 China 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：1997年第8卷第11期

页      面：957-960页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

主　　题：The Total Synthesis of Hinesol and Agarospirol 

摘      要：A mild base-catalyzed retro-benzilic acid rearrangement of a proto-[2+2]photocycloadduct, formed in highly steroselective photoaddition of methyl 2,4-dioxo-pentanoate to 1,5-dimethyl-6-methylenecyclohexene, afforded a spiro[4, 5] decenedione from which hinesol and agarospirol were synthesized by means of reductive elimination of α-diketone and C1-homologation.