Research Progress of Angiogenesis in Atherosclerotic Plaque in Chinese Medicine and Western Medicine

作     者：MA Lan DAI Jin CHEN Jie CAI Hong-wen LI Jia-ying LI Xin-yao CHEN Shen-jie MAO Wei 

作者机构：The First Affiliated Hospital of Zhejiang Chinese Medical UniversityHangzhou 310053China 

出 版 物：《Chinese Journal of Integrative Medicine》 (中国结合医学杂志（英文版）)

年 卷 期：2018年第24卷第12期

页      面：950-955页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：Supported by the National Natural Science Foundation of China(No.81673706) 

主　　题：angiogenesis atherosclerotic plaque Chinese medicine Western medicine 

摘      要：Angiogenesis in atherosclemtic plaque plays a critical role in the mechanism of atherosclerotic physiopathology. Present consensus shows that angiogenesis in atherosclerotic plaque is mainly resulted in hypoxia, inflammation and some pro-angiogenic factors. The homeostasis in plaque, which is hypoxic and infiltrated by inflammatory cells, may lead to angiogenesis, increase the plaque instability and the incidence rate of vascular events. This article reviews the progression of pathogenetic mechanism, physiopathological significance, relevant detecting technique and corresponding therapeutic methods of Chinese and Western medicine of angiogenesis in atherosclerotic plaque, so as to provide more theoretical basis for atherosclerotic clinical treatment.