Effects of benner pury on the function of endothelial progenitor cells in vitro from patients with hypertension in a time-dependent manner

作     者：Yongdong Li Huihua Wen Ruizhen Lian Gaole Alatan 

作者机构：Department of Cardiologythe Third Affiliated Hospital of Inner Mongolia Medical UniversityInner MongoliaChina College of Life ScienceInner Mongolia UniversityInner MongoliaChina 

出 版 物：《Discussion of Clinical Cases》 (临床病例讨论杂志（英文版）)

年 卷 期：2016年第3卷第1期

页      面：5-10页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Hypertension Endothelial progenitor cells Proliferation Migration Adhesion Apoptosis Oxidative stress 

摘      要：Objective:To investigate the effect of Benner Pury on Endothelial progenitor cells(EPCs)proliferation,migration,adhesion,apoptosis and oxidative stress in vitro from patients with hypertension and its time ***:The patients who were diagnosed as hypertension grade 1 according to the standard“Guidelines for Prevention and Treatment of Hypertensionwere *** cells were isolated by density gradient centrifugation and stained with fluorescence chemical acetylated low density lipoprotein marked with DiI(acLDL-DiI)and fluorescein isothiocyanate(FITC)-*** staining positive cells were considered as the differentiation of *** control group included healthy subjects matched with study group in age,*** cultivated for 5 days were used for *** harvested at different set times under the stimulation of Benner Pury,and the EPCs proliferation,migration,adhesion ability,apoptosis and oxidative stress indicators were detected ***:(1)Compared with the control group,peripheral blood EPCs proliferation,migration and adhesion ability were ob-viously decreased in the hypertension group(p.01),EPCs apoptosis rate and oxidative stress response were significantly increased(p.01).(2)Benner Pury significantly increased the EPCs proliferation,migration,adhesion ability and improved apoptosis and oxidative stress reaction in a time-dependent ***:Benner Pury can improve the EPCs proliferation,migration,adhesion,apoptosis and oxidative stress in patients with hypertension in a time-dependent manner.