Alpha-fetoprotein screening in patients with hepatitis C-induced cirrhosis who achieved a sustained virologic response in the direct-acting antiviral agents era

作     者：Marco Spadaccini Ana Lleo Roberto Ceriani Giovanni Covini Lorenza Rimassa Guido Torzilli Luca Di Tommaso Alessio Aghemo 

作者机构：Internal Medicine and Liver Unit Humanitas Research Hospital Department of Biomedical Sciences Humanitas University Medical Oncology and Hematology Unit Humanitas Clinical and Research Center Humanitas University Division of Hepatobiliary and General Surgery Department of Surgery Humanitas Clinical and Research Center - IRCCS Humanitas University Pathology Unit Humanitas Research Hospital 

出 版 物：《Hepatobiliary & Pancreatic Diseases International》 (国际肝胆胰疾病杂志（英文版）)

年 卷 期：2018年第17卷第6期

页      面：570-574页

核心收录：

学科分类：10[医学] 

主　　题：HCC AFP SVR Alpha-fetoprotein screening in patients with hepatitis C-induced cirrhosis who achieved a sustained virologic response in the direct-acting antiviral agents era 

摘      要：To the Editor:Hepatocellular carcinoma (HCC) is the most common primary livertumorandthethirdcauseofcancer-relateddeathsworldwide. HCC is the consequence of malignant transformation of hepatocytes and mainly occurs in patients with cirrhosis. Hepatitis C virus (HCV) chronic infection is a leading cause of end-stage liver diseaseandHCCintheWesterncountries[1].Theapprovalof direct-acting antiviral agents (DAAs) for the treatment of HCV has revolutionized the management of the disease, as no absolute contraindication to treatment exists and sustained virological response