OBSERVATION ON THE EFFECTS OF CHINESE MEDICINE ZHENXUANYIN FOR IMPROVING CEREBRAL BLOOD FLOW IN RATS WITH CEREBRAL ISCHEMIA

作     者：王静怡 Yasuhiro Magata Naoya Hattori Yoshiharu Yonekura Nagara Tamaki Fumiko Tanaka Junji Konishi Seok Rye Choi Shigeru Matsuzaki 

作者机构：Department of Nuclear Medicine Faculty of Medicine Kyoto University Japan Chemistry Department of Radio Medicine Faculty of Pharmacy Kyoto University Japan Department of Neurological Internal Medicine Faculty of Medicine Kyoto University Japan Mailing Address of Jingyi Wang: Department of Neurological Internal Medicine Hospital of Traditional Chinese Medicine Xi'an 710001 China 

出 版 物：《Journal of Traditional Chinese Medicine》 (中医杂志（英文版）)

年 卷 期：1997年第17卷第4期

页      面：299-303页

核心收录：

学科分类：1008[医学-中药学(可授医学、理学学位)] 1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 1005[医学-中医学] 1002[医学-临床医学] 100602[医学-中西医结合临床] 10[医学] 

主　　题：镇眩饮 

摘      要：Zhenxuanyin (镇眩饮) is composed of pure Chinese medicinal herbs, such as gastrodia tuber, poria cocos, ligusticum wallichii etc. 4-verssel occlusion (4VO) model rats were reperfused after 30 minutes’ complete occlusion, and Zhenxuanyin was administered 3 times a day. 24 hours later, 123I-IMP uptake in the brain was evaluated as an index of cerebral blood flow (CBF). The results show that Zhenxuanyin (0.03g kg, 0.3g kg, Ig kg, or 3g/ kg a day) can greatly improve the blood flow in the main cerebral regions, and 0.3g/ kg can increase cerebral blood flow (CBF) to the normal level.