Peroxisome proliferator-activated receptor γ ameliorates pulmonary arterial hypertension by inhibiting 5-HT2B receptor

作     者：Man Lung FUNG John Y-J SHYY 

作者机构：Department of PhysiologyLi Ka Shing Faculty of Medicinethe University of Hong KongHong KongChina Cardiovascular Research CenterXi'an Jiaotong UniversityXi'an 710061China 

出 版 物：《中国病理生理杂志》 (Chinese Journal of Pathophysiology)

年 卷 期：2012年第11期

页      面：2060-2060页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：NSFC/RGC Joint Research Scheme(No.N_CUHK428/09 .30931160434) tional Science Foundation of China(No.30890041) 

主　　题：ameliorates pulmonary arterial hypertension by inhibiting 5-HT PPAR Peroxisome proliferator-activated receptor receptor 

摘      要：AIM:An elevated plasma level of 5-hydroxytryptamine(5-HT)and/or upregulation of 5-HT receptor signaling are implicated in vascular contraction and remodeling in pulmonary arterial hypertension(PAH).Recently,peroxisome proliferator-activating recep-