Cytoskeleton Dynamics: A Continuum Cooperative Hydrolysis Model

作     者：胥建卫 程波 冯玉宇 汪自庆 王国栋 

作者机构：College of Science Northwest A&F University 

出 版 物：《Communications in Theoretical Physics》 (理论物理通讯（英文版）)

年 卷 期：2015年第63卷第5期

页      面：648-652页

核心收录：

学科分类：0710[理学-生物学] 081703[工学-生物化工] 07[理学] 08[工学] 0817[工学-化学工程与技术] 071009[理学-细胞生物学] 09[农学] 0901[农学-作物学] 0836[工学-生物工程] 090102[农学-作物遗传育种] 

基　　金：Supported by Chinese Universities Scientific Fund under Grant No.2014YB029 National Natural Science Foundation of China under Grant No.11205123 

主　　题：continuum model cooperative hydrolysis treadmilling 

摘      要：Cytoskeleton is a network of filamentous proteins, such as actin filaments and microtubules. We propose a continuum cooperative hydrolysis model which possesses exactly analytical solution to describe the dynamics of filament. The results show that the cooperativRy leads to non negative-exponential distribution of T （ATP or GTP） subunits. As an application, we investigate the treadmilling phenomenon using our model. It is shown that the cooperativity remarkably affects the length of filament.