NON-LINEAR OPTICAL IMAGING OF OBESITY-RELATED HEALTH RISKS:REVIEW

作     者：THUC T.LE JI-XIN CHENG 

作者机构：Weldon School of Biomedical Engineering Purdue University West LafayetteIndiana 47907USA Department of Chemistry and Weldon School of Biomedical Engineering Purdue University West LafayetteIndiana 47907USA 

出 版 物：《Journal of Innovative Optical Health Sciences》 (创新光学健康科学杂志（英文）)

年 卷 期：2009年第2卷第1期

页      面：9-25页

核心收录：

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 0808[工学-电气工程] 070207[理学-光学] 0809[工学-电子科学与技术（可授工学、理学学位）] 07[理学] 08[工学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0836[工学-生物工程] 0803[工学-光学工程] 0702[理学-物理学] 

基　　金：supported by a post-doctoral fellowship F32HL089074 to Le T.T. a NSF grant 0416785-MCB NIH grants R21 EB004966 and R01 EB007243 to Cheng J.X 

主　　题：Atherosclerosis coherent anti-Stokes Raman scattering lipid droplet mammary cancer non-linear optics obesity second harmonic generation sum-frequency generation twophoton fluorescence tumor stroma 

摘      要：This review highlights the recent applications of non-linear optical(NLO)microscopy to study obesity-related health risks.A strong emphasis is given to the applications of coherent anti-Stokes Raman scattering(CARS)microscopy where multiple non-linear optical imaging modalities including CARS,sum-frequency generation(SFG),and two-photon fluorescence are employed simultaneously on a single microscope *** examples on applications of NLO microscopy to study lipid-droplet biology,obesity-cancer relationship,atherosclerosis,and lipidrich biological structures are discussed.