Formation of Stable Lamellar Gel Structure Containing Pseudoceramide and Its Evaluation of Barrier Recovery Function
Formation of Stable Lamellar Gel Structure Containing Pseudoceramide and Its Evaluation of Barrier Recovery Function作者机构：Amorepacific Co.R&D Center Amorepacific (Shanghai) R&I Center Co.Ltd.
出 版 物：《China Detergent & Cosmetics》 (日用化学品科学（英文版）)
年 卷 期：2017年第2卷第2期
页 面：42-48页
学科分类：081702[工学-化学工艺] 08[工学] 0817[工学-化学工程与技术]
主 题：pseudoceramide lamellar gel structure skin barrier
摘 要：We formulated new skin care cosmetics with lamella structure in which high amount of pseudo-ceramides were incorporated. Consistency of this lamellar gel creams were checked for 1 month on various temperatures and for 1 year on RT. Generally, multi-lamellar emulsion shows typical Maltese cross on polarized microscope, but Maltese cross was not found in case of these creams; Multi-lamellar structure of the creams could be identifed by small-angle X-ray scattering （SAXS）. To evaluate skin barrier recovery function, we applied one of this creams and a vehicle cream to forearm skin which is tape-stripped to remove barrier layer to see if they infuence mass of molecules related to barrier function. 96 h after application, we found that this lamellar gel cream promoted synthesis of ceramides, amino acids and NMFs, thereby enhanced barrier recovery function.
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