Effect of Human Umbilical Vein Endothelial Cells on Immune Responses of Lipopolysaccharide-lnduced THP1 Macrophages

作     者：Zhou-Xin Yang Dong-Yang Guo An-Bang Wei Cai-Bao Hu Mo-Lei Yan Guo-Long Cai 

作者机构：Department of Critical Care Medicine Zhejiang Hospital Hangzhou Zhejiang 310013 China Department of Clinical Medicine Zhejiang University School of Medicine Hangzhou Zhejiang 310058 China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2018年第131卷第18期

页      面：2226-2228页

核心收录：

学科分类：1001[医学-基础医学(可授医学、理学学位)] 100102[医学-免疫学] 10[医学] 

基　　金：This study was supported by grants from the National Natural Science Foundation of China (No. 81772051) and Zhejiang Provincial Natural Science Foundation of China (No. LQ16CI20001) 

摘      要：To the Editor： Sepsis is one of the leading causes of death in Intensive Care Units. It is known as the syndrome of organ dysfunction caused by infection. Immune response has a critical role in sepsis. High concentrations of pro-inflammatory cytokines such as tumor necrosis factor alpha （TNF-α） and interleukin （IL）-6 have been suggested to be harmful and one of the major causes of organ injury.[1] Immune paralysis in sepsis causes a secondary infection.