Predictive value of red cell distribution width on left atrial thrombus or left atrial spontaneous echo contrast in patients with non-valvular atrial fibrillation

作     者：Xian-Zhang ZHAN Wei-Dong LIN Fang-Zhou LIU Yu-Mei XUE Hong-Tao LIAO Xin LI Xian-Hong FANG Hai DENG Jun HUANG Yang-Qiu LI Jo-Jo HAI Hung-Fat Tse Shu-Lin WU 

作者机构：Department of Hematology the First Affiliated Hospital Jinan University Guangzhou China Department of Cardiology Atrial Fibrillation Center Guangdong Cardiovascular Institute Guangdong General Hospital Guangdong Academy of Medical Sciences Guangzhou China Cardiology Division Department of Medicine Queen Mary Hospital the University of Hong Kong Hong Kong China Division of Cardiology Department of Medicine the University of Hong Kong Shenzhen Hospital Shenzhen China 

出 版 物：《Journal of Geriatric Cardiology》 (老年心脏病学杂志（英文版）)

年 卷 期：2018年第15卷第6期

页      面：408-412页

核心收录：

学科分类：090801[农学-水产养殖] 0832[工学-食品科学与工程（可授工学、农学学位）] 0908[农学-水产] 08[工学] 09[农学] 083202[工学-粮食、油脂及植物蛋白工程] 

基　　金：We appreciated Xuan Jiang for the statistical analysis. This work was supported by National Nature Science Foundation of China (No.81370295)  Science and Technology Program of Guangdong Province  China (No. 2017A02 0215054)  Science and Technology Planning of Guangzhou City  China (No.2014B070705005). The authors declared no potential conflicts of interest with respect to the research  authorship or publication of this article 

主　　题：Atrial fibrillation Left atrial spontaneous echo contrast Left atrial thrombus Red cell distribution width 

摘      要：Objective To evaluate the predictive value of red cell distribution width （RDW） on left atrial thrombus （LAT） or left atrial spontane- ous echo contrast （LASEC） in patients with non-valvular atrial fibrillation （AF）. Methods We reviewed 692 patients who were diagnosed as non-valvular AF and underwent transesophageal echocardiography （TEE） in Guangdong Cardiovascular Institute from April 2014 to December 2015. The baseline clinical characteristics, laboratory test of blood routine, electrocardiograph measurements were analyzed. Results Eighty-four patients were examined with LAT/LASEC under TEE. The mean RDW level was significantly higher in LAT/LASEC patients compared with the non-LAT/LASEC patients （13.59% ± 1.07% ws. 14.34% ± 1.34%; P 〈 0.001）. Receiver-operating characteristic curve analysis was performed and indicated the best RDW cut point was 13.16%. Furthermore, multivariate logistic regression analysis indicated that RDW level 〉 13.16% could be an independent risk factor for LAT/LASEC in patients with AF. Conclusion Elevated RDW level is associated with the presence of LAT/LASEC and could be with moderate predictive value for LAT/LASEC in patients with non-valvular AF.