Evaluation of Early Warning Indicators of ARV Resistance to HIV in the Hospital of Tivaouane from 2008 to 2016

作     者：Agbogbenkou Tévi Déla-dem Lawson Ndeye Astou Lakhe Haby Dione Papa Souleymane Toure Mamadou Ba Ndeye Biram Niang Bernard Marcel Diop Sylvie Audrey Diop-Nyafouna 

作者机构：Department of Health Thies University Thies Senegal Infectious and Tropical Diseases Department Fann Teaching University Hospital Dakar Senegal 

出 版 物：《Advances in Infectious Diseases》 (传染病进展（英文）)

年 卷 期：2018年第8卷第2期

页      面：54-63页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：HIV Resistance EWI Tivaouane 

摘      要：Introduction: HIV resistance to antiretroviral is currently a global concern, and requires increased surveillance in a context of widespread ARV treatment. Objective: To evaluate early warning indicators of HIV resistance to ARVs in the Hospital of Tivaouane (Senegal) where viral load was not routinely available. Methods: This is a cross-sectional retrospective study from 2008-2016. The etraction tool (May 2010 version) was used to analyze the EWI. Results: We collected 360 HIV positive patients followed on average for 3.57 years ± 3.02. 2009, 2010 and 2012 recorded 100% ARV prescribing rates. Throughout the study period, the percentage of patients lost to follow-up during the first 12 months of treatment was less than 20%. Virtually, all patients were still under primary ARVT over 12-month treatment. All patients (100%) withdrew their ARV drugs on time. No stock storage regarding various classes of ARVs was noted during the study period. Conclusion: At the end of this study we recommend to maintain regular follow-up of EWI, and combine it with the achievement of viral load.