Diterpenoid UDP-Glycosyltransferases from Chinese Sweet Tea and Ashitaba Complete the Biosynthesis of Rubusoside

作     者：Yuwei Sun Zhuo Chen Jianxu Li Jianhua Li Huajun LV Jingya Yang Weiwei Li Dingan Xie Zhiqiang Xiong Peng Zhang Yong Wang 无

作者机构：CAS-Key Laboratory of Synthetic Biology CAS Center for Excellence in Molecular Plant Sciences Institute of Plant Physiology and Ecology Chinese Academy of Sciences Shanghai 200032 China National Key Laboratory of Plant Molecular Genetics CAS Center forExcellence in Molecular Plant Sciences Institute of Plant Physiology and Ecology Chinese Academy of Sciences Shanghai 200032 China University of Chinese Academy of Sciences Beijing 100039 China College of Food Science and Technology Shanghai Ocean University Shanghai 201306 China 

出 版 物：《Molecular Plant》 (分子植物（英文版）)

年 卷 期：2018年第11卷第10期

页      面：1308-1311页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 09[农学] 071007[理学-遗传学] 0901[农学-作物学] 0902[农学-园艺学] 090102[农学-作物遗传育种] 090201[农学-果树学] 

基　　金：This work was supported by the National Natural Science Foundation of China (grant nos. 31670099  31700261)  the Key Basic Research Project of Shanghai Science and Technology Commission (grant no. 14JC1406900)  the Key Research Program of the Chinese Academy of Science (grant nos. XDPB0400  KFZD-SW-212  KFZD-SW-215) and the Strategic Priority Research Program "Molecular mechanism of Plant Growth and Development" of CAS. This work was also financiaTly supported by the National Key Laboratory of Plant Molecular Genetics  SIPPI. CAS 

主　　题：PLANT METABOLISM GLYCOSIDES CHINGII 

摘      要：Dear Editor, Diterpenoids are important molecules that play significant roles in many biological processes. In plants, acyclic diterpene phytol is a representative side chain of chlorophyll, and tetracyclic diterpene gibberellins ubiquitously serve as plant hormones regulating growth and development. Decoration of diterpene core struc-tures by oxidation and glycosylation are usually key steps to confer final bioactivity of diterpenoid compounds. In contrast to the extensively studied oxidases involved in gibberellin biosyn- thesis, diterpenoid-related glycosyltransferases have been scarcely documented, possibly due to the relative rarity of diter- pene glycosides in the plant kingdom. Only a few UDP-dependent glycosyltransferases （UGTs） have been characterized to participate in diterpene glycoside biosynthesis （Richman et al., 2005; Nagatoshi et al., 2012）.