Lacrimal gland tumors in Turkey：types,frequency,and outcomes

作     者：Yagmur Seda Yesiltas Ahmet Kaan Gundiiz Esra Erden Carol L. Shields 

作者机构：Department of Ophthalmology Ankara University Faculty of Medicine Ankara 06620 Turkey Department of Pathology Ankara University Faculty of Medicine Ankara 06230 Turkey Ocular Oncology Service Wills Eye Hospital Thomas Jefferson University Philadelphia PA 19107 USA 

出 版 物：《International Journal of Ophthalmology(English edition)》 (国际眼科杂志（英文版）)

年 卷 期：2018年第11卷第8期

页      面：1296-1302页

核心收录：

学科分类：1002[医学-临床医学] 0806[工学-冶金工程] 08[工学] 

主　　题：orbit lacrimal gland tumor inflammation epithelial tumor non-epithelial tumor 

摘      要：AIM： To evaluate the clinical, radiological, and treatment features of lacrimal gland ***： Retrospective review of 99 eyes of 92 patients with lacrimal gland tumors diagnosed and managed in a single institution between January 1999 and March 2017. Clinical and radiological features, histopathology, treatment methods, and prognosis were ***： The mean patient age was 40.3（range： 7-80）*** diagnosis was made histopathologically in 91（91.9%） tumors and on a clinical and radiological basis in 8（8.1%） tumors. Final diagnoses included idiopathic orbital inflammation（pseudotumor） in 46（46.5%） lesions, pleomorphic adenoma in 14（14.1%）, adenoid cystic carcinoma in 12（12.1%）, granulomatous inflammation in 10（10.1%）, lymphoma in 5（5.0%）, benign reactive lymphoid hyperplasia in 3（3.0%）, dacryops in 3（3.0%）, carcinoma ex pleomorphic adenoma in 2（2.0%）, adenocarcinoma in 1（1.0%）, dermoid cyst in 1（1.0%）, cavernous hemangioma in 1（1.0%）, and leukemic infiltration in 1（1.0%）. Nonepithelial tumors comprised 64.6%（n=64） of all lacrimal gland tumors, epithelial tumors 32.3%（n=32）, dermoid cyst 1%（n=1）, cavernous hemangioma 1%（n=1）, and leukemic infiltration 1%（n=1）. There were in total 78（78.8%） benign and 21（21.2%） malignant tumors. CONCLUSION： Overall, 65% of lacrimal gland tumors were of non-epithelial origin and 32% of epithelial origin. By histopathology and clinical evaluation, 79% of lacrimal gland tumors were benign. The most common lacrimal gland tumors include idiopathic orbital inflammation（46.5%）, epithelial（32.3%）, and lymphoproliferative（8.1%） lesions.