A photoacoustic imaging system with variable gain at different depths
作者机构：Shenzhen Key Laboratory for Minimal Invasive Medical Technologies Graduate School at Shenzhen Tsinghua UniversityShenzhen 518055P.R.China Department of Biomedical Engineering Tsinghua UniversityBeijing 100084P.R.China Center of Precision Medicine and Healthcare Tsinghua-Berkeley Shenzhen InstituteShenzhen 518055P.R.China Shenzhen Wisonic Medical Technology Co.Ltd.Taoyuan StreetNanshan DistrictShenzhen 518055P.R.China
出 版 物：《Journal of Innovative Optical Health Sciences》 (创新光学健康科学杂志（英文）)
年 卷 期：2018年第11卷第5期
页 面：1-10页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金：the financial support fromNational Natural Science Foundation of China(NSFC)(61675113,61527808,81401539,and 31271056) Science and Technology Research Program of Shenzhen City(JSGG20150331151536448,JCYJ20160428182247170,and JCYJ20170412170255060) Shenzhen basic research layout project(JCYJ20160324163759208) the projects in Shenzhen Medical Engineering Laboratory For Human Auditory-equilibrium Function
主 题：Photoacoustic imaging variable gain imaging depth
摘 要：We established a photoacoustic imaging(PAI)system that can provide variable gain at different *** PAI system consists of a pulsed laser with an optical parametric oscillator working at a 728 nmwavelength and an imaging-acquisition-and-processing unit with an ultrasound ***-controlled attenuator was used to realize variable gain at different depths when acquiring PAI *** proof-of-concept imaging results for variable gain at different depths were achieved using specic *** resolution and optical contrast obtained through the results of variable gain for a targeted depth range are better than those of constant gain for all *** further testify the function,we imaged the sagittal section of the body of in vivo nude *** addition,we imaged an absorption sample embedded in a chicken breast tissue,reaching a maximum imaging depth of4.6 *** results obtained using the proposed method showed better resolution and contrast than when using 50 dB gain for all *** depth range resolution was1 mm,and the maximum imaging depth of our system reached4.6 ***,blood vessels can be revealed and targeted depth range can be selected in nude mice imaging.
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