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A photoacoustic imaging system with variable gain at different depths

作     者:Tian Guan Yao Li Muqun Yang Yong Jiang Yonghong He 

作者机构:Shenzhen Key Laboratory for Minimal Invasive Medical Technologies Graduate School at Shenzhen Tsinghua UniversityShenzhen 518055P.R.China Department of Biomedical Engineering Tsinghua UniversityBeijing 100084P.R.China Center of Precision Medicine and Healthcare Tsinghua-Berkeley Shenzhen InstituteShenzhen 518055P.R.China Shenzhen Wisonic Medical Technology Co.Ltd.Taoyuan StreetNanshan DistrictShenzhen 518055P.R.China 

出 版 物:《Journal of Innovative Optical Health Sciences》 (创新光学健康科学杂志(英文))

年 卷 期:2018年第11卷第5期

页      面:1-10页

核心收录:

学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基  金:the financial support fromNational Natural Science Foundation of China(NSFC)(61675113,61527808,81401539,and 31271056) Science and Technology Research Program of Shenzhen City(JSGG20150331151536448,JCYJ20160428182247170,and JCYJ20170412170255060) Shenzhen basic research layout project(JCYJ20160324163759208) the projects in Shenzhen Medical Engineering Laboratory For Human Auditory-equilibrium Function 

主  题:Photoacoustic imaging variable gain imaging depth 

摘      要:We established a photoacoustic imaging(PAI)system that can provide variable gain at different *** PAI system consists of a pulsed laser with an optical parametric oscillator working at a 728 nmwavelength and an imaging-acquisition-and-processing unit with an ultrasound ***-controlled attenuator was used to realize variable gain at different depths when acquiring PAI *** proof-of-concept imaging results for variable gain at different depths were achieved using specic *** resolution and optical contrast obtained through the results of variable gain for a targeted depth range are better than those of constant gain for all *** further testify the function,we imaged the sagittal section of the body of in vivo nude *** addition,we imaged an absorption sample embedded in a chicken breast tissue,reaching a maximum imaging depth of4.6 *** results obtained using the proposed method showed better resolution and contrast than when using 50 dB gain for all *** depth range resolution was1 mm,and the maximum imaging depth of our system reached4.6 ***,blood vessels can be revealed and targeted depth range can be selected in nude mice imaging.

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