Analysis of 8 chronic kidney disease patients complicated with Pneumocystis carinii pneumonia

作     者：Shan Lu Li Yao Dan-dan Wei Ya-bin Jiao Mei-na Liu Li-ning Wang 

作者机构：Department of Nephrology the First Affiliated Hospital of China Medical University Shenyang Liaoning110001 P.R.China 

出 版 物：《中国现代医学杂志》 (China Journal of Modern Medicine)

年 卷 期：2011年第21卷第3期

页      面：371-376页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Pneumocystis carinii pneumonia chronic kidney disease immunosuppressive treatment 

摘      要：Objective To study the clinical characteristics and outcome of Pneumocystis carinii pneumonia(PCP) in patients with chronic kidney *** Clinical data of 8 cases of chronic kidney diseases complicated with PCP(excluding renal transplant patients) were examined *** The most common presenting symptoms at admission were fever(100%),cough without or with a little sputum(87.5%),and exertional dyspnea(75%).Beside these,they complained of chest tightness,fatigue,sweating and *** patients(75%) presented with hypoxemia were diagnosed with type 1 respiratory failure during the course of *** most common CT feature was bilateral patchy areas of ground-glass *** patients had peripheral blood lymphocyte count less than 1 ×109/*** patients had CD4 cell count less than 200/*** LDH level was elevated in 5 patients(582±222.55).Among the 8 patients,2 patients died within 20 days of PCP *** Pneumocystis carinii pneumonia is an opportunistic and serious complication in chronic kidney disease patients treated with *** disease progression is fast and patients with respiratory failure have a high mortality *** diagnosis and appropriate treatment are important for better prognosis.