Aqueous levels of erythropoietin in acute retinal vein occlusion with macular edema
Aqueous levels of erythropoietin in acute retinal vein occlusion with macular edema作者机构：Department of Ophthalmology Konkuk University Medical Center Konkuk University School of Medicine Gongdeok Seoul Eye Clinic
出 版 物：《International Journal of Ophthalmology(English edition)》 (国际眼科杂志（英文版）)
年 卷 期：2014年第7卷第3期
页 面：501-506页
核心收录：
学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学]
主 题：aqueous level of erythropoietin acute retinal vein occlusion retinal ischemia macular edema
摘 要：AIM:To investigate the aqueous erythropoietin(EPO)levels and associated factors in patients with acute retinal vein occlusion(RVO).METHODS:The aqueous EPO level was measured in patients with macular edema(ME)secondary to acute branched retinal vein occlusion(BRVO)or central retinal vein occlusion(CRVO).Aqueous fluid from cataract patients served as the *** also evaluated whether aqueous level of EPO was associated with factors such as serum EPO level,non-perfusion area,central macular thickness(CMT),and arterio-venous(AV)transit timeRESULTS:Twenty-seven RVO patients(16 BRVO,11CRVO)and 9 control subjects were enrolled in the *** aqueous EPO level(mU/mL)was higher in RVO(68.2±54.3)than that in the control subjects(12.9±5.9).More specifically,the aqueous EPO level was higher in CRVO(118.9±52.1)than that in BRVO(33.3±10.8).However,no differences were found in serum EPO levels among three *** in RVO patients had a positive correlation with the aqueous EPO level(r=0.66).Also,in terms of non-perfusion area,the aqueous EPO levels were more elevated in the ischemic subgroup than in the non-ischemic subgroup in both BRVO and ***:Aqueous EPO levels are elevated in patients with macular edema secondary to recent onset *** with CRVO have higher EPO levels than those with *** aqueous EPO level in RVO has a positive correlation with CMT and is associated with non-perfusion *** results suggest that the aqueous EPO level could be associated with retinal ischemia and may be involved in the pathogenesis of macular edema secondary to RVO.
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