CAPABILITY OF DNA-FUELED MOLECULAR MACHINE IN TUNING ASSOCIATION RATE OF DNA-FUNCTIONALIZED GOLD NANOPARTICLES

作     者：Ting-jie Song Hao-jun Liang 

作者机构：CAS Key Laboratory of Soft Matter Chemistry Hefei National Laboratory for Physical Sciences at the Microscale Department of Polymer Science and Engineering University of Science and Technology of China 

出 版 物：《Chinese Journal of Polymer Science》 (高分子科学（英文版）)

年 卷 期：2013年第31卷第9期

页      面：1183-1183,1184-1189页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070305[理学-高分子化学与物理] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0703[理学-化学] 

基　　金：supported by the National Natural Science Foundation of China (Nos. 20934004 and 91127046) the National Basic Research Program of China (NBRPC) (Nos. 2012CB821500 and 2010CB934500) 

主　　题：Assembly DNA Enhancing Kinetics Nanoparticle. 

摘      要：The capability of our newly developed DNA-machine-driven strategy in tuning the association rate of DNA- AuNPs was compared with that of linker-addition strategy which has potential practical applications in different fields. The new established strategy shows its superiority to the linker-addition strategy in tuning the association rate of DNA-AuNPs in both pre-incubation treatment and non-incubation treatment conditions since its two components （a complex and a catalyst- oligonucleotide） can be individually optimized to make the machine run at an optimal rate. This strategy will provide a more convenient and flexible option in designing an oligonucleotide detection system and building a complex and versatile device.