雌激素的血管作用:快速作用,新的机制和治疗潜力<英文>
Vascular effects of estrogens: rapid actions, novel mechanisms, and potential therapeutic implications作者机构:Cardiology University Hospital Zurich and Cardiovascular Research Laboratory Institute of Physiology University of Zurich CH-8091 Zurich Switzerland
出 版 物:《中国药理学报》 (Acta Pharmacologica Sinica)
年 卷 期:1999年第20卷第8期
页 面:682-690页
核心收录:
学科分类:1007[医学-药学(可授医学、理学学位)] 10[医学]
基 金:Project supported by the Deutsche Forschungsgemeinschaft the Swiss Heart Foundation and the ADUMED Foundation
摘 要:Although estrogen-dependent effects on thevasculature were first observed more than a centuryago, many of the mechanisms by which estrogensinteract with the vascular wall have been identified onlyin the past 15 years. Estrogens bind to vascularestrogen receptors (ER), including the ERα, the novelERβ as well as to membrane-bound receptors.