Biomechanical response of skeletal muscle to eccentric contractions

作     者：Richard L.Lieber 

作者机构：Shirley Ryan Ability Lab Department of Veterans Affairs Departments of Biomedical Engineering and PhysiologyNorthwestern University 

出 版 物：《Journal of Sport and Health Science》 (运动与健康科学（英文）)

年 卷 期：2018年第7卷第3期

页      面：294-309页

核心收录：

学科分类：1002[医学-临床医学] 100216[医学-运动医学] 10[医学] 

主　　题：Cytoskeleton Eccentric contraction Inflammation Muscle injury Muscle mechanics 

摘      要：The forced lengthening of an activated skeletal muscle has been termed an eccentric contraction(EC).This review highlights the mechanically unique nature of the EC and focuses on the specific disruption of proteins within the cell known as cytoskeletal *** major intermediate filament cytoskeletal protein,desmin,has been the focus of work in this area because changes to desmin occur within minutes of ECs and because desmin has been shown to play both a mechanical and biologic role in a muscle s response to *** is hoped that these types of studies will assist in decreasing the incidence of muscle injury in athletes and facilitating the development of new therapies to treat muscle injuries.