工作受限和生产力丧失与银屑病患者健康相关的生活质量有关而与临床严重度无关
Work limitations and productivity loss are associated with health-related quality of life but not with clinical severity in patients with psoriasis作者机构：Department of DermatologyUniversity Hospital Carl Gustav Carus Technical University Dresden Fetscherstrasse 74 DE-01307 Dresden GermanyDr.
出 版 物：《世界核心医学期刊文摘（皮肤病学分册）》 (Digest of the World Core Medical JOurnals:Dermatology)
年 卷 期：2006年第2卷第11期
页 面：53-54页
学科分类：1002[医学-临床医学] 100206[医学-皮肤病与性病学] 10[医学]
主 题：银屑病 严重度 生活质量 生物制剂 互联网广告 药物经济学 指导方针 中有
摘 要：Background: According to current guidelines the cost of productivity loss should be considered in pharmacoeconomic analyses. The cost of health-related productivity loss in psoriasis patients is unknown. Objective: To estimate the cost of productivity loss in psoriasis and its association with healthrelated quality of life and clinical disease severity. Methods: Cross-sectional study, recruitment of adult participants through Internet advertisements. 201 (72.3%) out of 278 eligible participants completed the study. Health-related work productivity loss, quality of life and clinical severity of psoriasis were assessed by standardized instruments. Results: Indirect costs of productivity loss clearly exceed the total direct cost. In contrast to objective clinical disease severity, health-related quality of life (measured by the Dermatology Life Quality Index) is an independent predictor of work productivity. Conclusions: There is good reason to believe that intervention can reduce health-related productivity loss by improving patients’quality of life. Savings from increased work productivity might offset comparatively high acquisition costs of biological agents.
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