外阴癌功能评价的可靠性及有效性

作     者：Janda M Obermair A Cella D 成夜霞 

作者机构：Queensland Cancer Fund PO Bo x 201 Spring Hill QLD 4004 Australia 

出 版 物：《世界核心医学期刊文摘（妇产科学分册）》 (Core Journal in Obstetrics/Gynecology)

年 卷 期：2005年第1卷第10期

页      面：32-32页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：功能评价 生活质量 反应曲线 等级评分 患者健康状况 临床实践 α值 信度系数 内部一致性 快速测量 

摘      要：Objectives. To assess the reliability and validity of the Functional Assessment of Cancer Therapy- Vulvar (FACT- V). Methods. Seventy- seven patients treated between January 1996 and January 2001 for cancer of the vulva completed the FACT- V, the Eastern Cooperative Oncology Group Performance Status Rating (ECOG- PSR) and the Hospital Anxiety and Depression Scale (HADS) once, 20 consecutive patients treated between February 2001 and October 2001 completed the questionnaires twice, once before surgery and at 2 months follow- up. The FACT- V scores were compared by patients’ performance status, FIGO stage, recurrence, and age, and correlated to the HADS scores. Changes in the FACT- V from baseline to 2 months follow- up were evaluated to establish FACT- V’s responsiveness to change. Results. The FACT- V’s internal consistency was adequate (Chronbach’s alpha range, 0.75 to 0.92). Patients with lower performance status, higher FIGO- stage or recurrent disease received lower FACT- V scores, indicating discriminant validity. The correlation between the FACT- V and the HADS were in the expected direction, indicating convergent and divergent validity. From pre- to postsurgery, scores in nine out of fifteen items of the vulvar cancer- specific subscale improved, while those of five items declined, indicating sensitivity of the vulvar cancer specific items to changes in patients’ well- being. Conclusions. The newly developed FACT- V provides a reliable and valid assessment of the quality of life of women with vulvar cancer. It can be used as a short measure of quality of life within research studies, and to facilitate communication about quality of life issues in clinical practice.