Studies on the Components of Crude and Processed Fructus Corni by ESI-MS^n

作     者：ZHOU Li-li WU Guo-guang LIU Zhi-qiang LIU Shu-ying 

作者机构：China University of Mining and Technology Xuzhou 221008 P R. China Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun Center of Mass Spectrometry Changchun 130022 P R. China 

出 版 物：《Chemical Research in Chinese Universities》 (高等学校化学研究（英文版）)

年 卷 期：2008年第24卷第3期

页      面：270-274页

核心收录：

学科分类：100703[医学-生药学] 1007[医学-药学(可授医学、理学学位)] 10[医学] 

基　　金：the National Natural Science Foundation of China(No.30672600) the Great Research Project of Chinese Academy of Sciences(No.KGCX2-SW-213-06) the Natural Science Foundation of Jilin Province(No.20060902) the Natural Science Foundation of Changchun City, China(No.04-02GG233) 

主　　题：Fructus Corni ESI-MSn Processed 

摘      要：The components of crude and processed Fructus Corni were investigated by means of electrospray ionization-tandem mass spectrometry（ESI-MSn） technique in the negative ion mode. Compared with those of crude Fructus Corni, the chemical components of the processed Fructus Corni were changed both in quality and in quantity. From the ESI-MS spectra of the crude and processed Fructus Corni, six peaks were selected to establish the characte-ristic ESI-MS peaks. Several factors in the processing procedure were examined. The experimental results demonstrate that the chemical reactions that occurred in the processing procedure can be used for the elucidation of the processed mechanism of Fructus Corni, which is regularly affected by the processing conditions. The present article provides both the chemistry evidence for the understanding of the processing procedure of Fructus Corni and the specific methodology for the research of the processing procedure and quality identification of traditional Chinese medicine.