Three minor new compounds from the aerial parts of Leonurus japonicus

作     者：Wei-Mao Zhong Zhao-Meng Cui Zhi-Ke Liu Yan Yang Da-Rong Wu Shao-Hua Liu Hui Long Han-Dong Sun Yong-Jun Dang Wei-Lie Xiao 

作者机构：State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of Botany Chinese Academy of Sciences University of Chinese Academy of Sciences Key Laboratory of Molecular Medicine Ministry of Education and Department of Biochemistry and Molecular Biology Fudan University Shanghai Medical College Chengdu No.1 Pharmaceutical Group Co. Ltd. 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2015年第26卷第8期

页      面：1000-1003页

核心收录：

学科分类：1008[医学-中药学(可授医学、理学学位)] 0703[理学-化学] 10[医学] 

基　　金：supported financially by National Natural Science Foundation of China(Nos.81422046 and 31300293) the National Science and Technology Support Program of China(No.2013BAI11B02) the Natural Science Foundation of Yunnan Province(No.2012FB178) the project sponsored by SRF for ROCS,SEM to W.L.Xiao 

主　　题：Leonurus japonicus Diterpenoid lonone derivative Jurkat IL2 secretion 

摘      要：Phytochemical investigation of the aerial parts of Leonurus japonicus led to the isolation of one new labdane diterpenoid, leojaponin D （1） and two new ionone derivatives, leojaponones A and B （2 and 3）, together with seven known diterpenoids （4-10）. Their structures were elucidated by extensive 1D and 2D NMR spectroscopic data and by comparison with data reported in the literature. Selected isolates were evaluated their effects on lurkat IL2 secretino.