Extrahepatic immune related manifestations in chronic hepatitis C virus infection

作     者：Maria Tampaki John Koskinas 

作者机构：Academic Department of MedicineMedical School of AthensHippokration General Hospital 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2014年第20卷第35期

页      面：12372-12380页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学] 

主　　题：Hepatitis C virus Autoimmune Extrahepatic manifestations Cryoglobulinemia 

摘      要：The association of chronic hepatitis C with immune related syndromes has been frequently *** is a great range of clinical manifestations affecting various systems and organs such as the skin,the kidneys,the central and peripheral nervous system,the musculoskeletal system and the endocrine *** the high prevalence of immune related syndromes in patients with chronic hepatitis C,the exact pathogenesis is not always *** have been often associated with mixed cryoglobulinemia,a common finding in chronic hepatitis C,cross reaction with viral antigens,or the direct effect of virus on the affected *** aim of this review is to analyze the reported hepatitis C virus immune mediated syndromes,their prevalence and clinical manifestations and to discuss the most supported theories regarding their pathogenesis.