Management of small hepatocellular carcinoma in cirrhosis:Focus on portal hypertension

作     者：Virginia Hernandez-Gea Fanny Turon Annalisa Berzigotti Augusto Villanueva 

作者机构：Hepatocellular Carcinoma Translational Research LaboratoryBarcelona-Clinic Liver Cancer GroupInstitut d'Investigacions Biomediques August Pi i SunyerLiver UnitHospital Clinic08036 BarcelonaSpain Hepatic Hemodynamic LaboratoryLiver UnitHospital ClinicUniversity of Barcelona08036 BarcelonaSpain Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y DigestivasInstituto Carlos Ⅲ08036 BarcelonaSpain 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2013年第19卷第8期

页      面：1193-1199页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Portal hypertension Hepatic venous pressure gradient Clinically significant portal hypertension Liver stiffness Liver cancer Hepatocellular carcinoma Resection Radiofrequency ablation Percutaneous ethanol injection 

摘      要：The incidence of hepatocellular carcinoma(HCC) is rising worldwide being currently the fifth most common cancer and third cause of cancer-related *** detection of HCC through surveillance programs have enabled the identification of small nodules with higher frequency,and nowadays account for 10%-15% of patients diagnosed in the West and almost 30% in *** with small HCC can be candidates for potential curative treatments:liver transplantation,surgical resection and percutaneous ablation,depending on the presence of portal hypertension and *** review will analyze recent advancements in the clinical management of these individuals,focusing on issues related to the role of portal hypertension,the debate between resection and ablative therapies and the future impact of molecular technologies.