Multi-responsive hydrogels for drug delivery and tissue engineering applications

作     者：Jennifer M.Knipe Nicholas A.Peppas 

作者机构：Department of Chemical EngineeringC0400The University of Texas at AustinAustinTX 78712USA Department of Biomedical EngineeringC0800The University of Texas at AustinAustinTX 78712USA College of PharmacyC0400The University of Texas at AustinAustinTX 78712USA 

出 版 物：《Regenerative Biomaterials》 (再生生物材料（英文版）)

年 卷 期：2014年第1卷第1期

页      面：57-65页

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070305[理学-高分子化学与物理] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0703[理学-化学] 

基　　金：Preparation of this review article was supported in part by the National Science Foundation Graduate Research Fellowship Program[DGE-1110007 to J.M.K.] 

主　　题：hydrogels intelligent polymers regenerative medicine drug delivery 

摘      要：Multi-responsive hydrogels,or‘intelligent’hydrogels that respond to more than one environmental stimulus,have demonstrated great utility as a regenerative biomaterial in recent *** are structured biocompatible materials that provide specific and distinct responses to varied physiological or externally applied *** evidenced by a burgeoning number of investigators,multi-responsive hydrogels are endowed with tunable,controllable and even biomimetic behavior well-suited for drug delivery and tissue engineering or regenerative growth *** article encompasses recent developments and challenges regarding supramolecular,layer-by-layer assembled and covalently cross-linked multi-responsive hydrogel networks and their application to drug delivery and tissue engineering.