Ethnomedicinal, phytochemical and pharmacological updates on Hygrophila auriculata (Schum.) Hiene： an overview

作     者：Neeraj K. Sethiya Nasir M. Ahmed Raeesh M. Shekh Vivek Kumar Pawan Kumar Singh Vipin Kumar 

作者机构：National Innovation Foundation-India Amrapur Crambharti Mahudi Road Candhinagar 382 650 Gujarat India 

出 版 物：《Journal of Integrative Medicine》 (结合医学学报（英文版）)

年 卷 期：2018年第16卷第5期

页      面：299-311页

核心收录：

学科分类：100703[医学-生药学] 1007[医学-药学(可授医学、理学学位)] 10[医学] 

主　　题：Ethnomedicine Hygrophila auriculata Pharmacology Phytochemical 

摘      要：This article explores the most recent evidence-based information on ethnomedicinal, phytochemical and pharmacological understanding of Hygrophila auriculata for the treatment of various diseases and health conditions. Various ethnomedicinal writings suggest the use of the plant or its parts for the treatment of jaundice, oedema, gastrointestinal ailments, diarrhoea, dysentery, urinogenital disorder, gall stones, urinary calculi, kidney stone, leucorrhoea, rheumatism, tuberculosis, anaemia, body pain, constipation, skin disease, and as an aphrodisiac. The plant has been reported to contain flavonoids （apigenin, luteolin, ellagic acid, gallic acid and quercetin）, alkaloids （asteracanthine and asteracanthicine）, triterpenes （lupeol, lupenone, hentricontane and betulin）, sterols （stigmasterol and asterol）, minerals, amino acids, fatty acids, aliphatic esters and essential oils. Extracts and bioactive compounds from the plant have been found to possess antimicrobial, anthelmintic, antitermite, nephroprotective, hepatoprotective, central nervous system protective, antitumour, antidiabetic, anticataract, antioxidant, haematopoietic, diuretic, antinociceptive, anti-inflammatory, antipyretic, antimotility, aphrodisiac, neuroprotection, anti- endotoxin and anti-urolithiatic activities. For this paper, we reviewed patents, clinical studies, analytical studies and marketed formulations from the earliest found examples from 1887 to the end of 2017.