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Effect of cerium ion on the proliferation,differentiation and mineralization function of primary mouse osteoblasts in vitro

Effect of cerium ion on the proliferation,differentiation and mineralization function of primary mouse osteoblasts in vitro

作     者:张金超 刘翠莲 李亚平 孙静 王鹏 邸科前 赵燕燕 

作者机构:Chemical Biology LaboratoryCollege of Chemistry & Environmental ScienceHebei University Affiliated Hospital of Hebei University Experimental CenterHebei University 

出 版 物:《Journal of Rare Earths》 (稀土学报(英文版))

年 卷 期:2010年第28卷第1期

页      面:138-142页

核心收录:

学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基  金:supported by the Natural Science Foundation of China (20971034) Foundation for Key Program of Ministry of Education of China (208018) Returned Scholars of Hebei Province (207041) Natural Science Foundation of Hebei Province (B2009000161) Natural Science Foundation of Hebei University 

主  题:cerium ion osteoblasts proliferation differentiation mineralization rare earths 

摘      要:The effects of cerium ion(Ce3+) on the proliferation,differentiation,adipocytic transdifferentiation and mineralization function of primary mouse osteoblasts(OBs) were *** results indicated that Ce3+ at all concentrations(1×10-9,1×10-8,1×10-7,1×10-6,1×10-5,and 1×10-4 mol/L) promoted the proliferation of osteoblasts(OBs).On day 1 and 3,Ce3+ promoted the differentiation of OBs at concentrations of 1×10-9,1×10-7,and 1×10-6 mol/L,but inhibited the differentiation of OBs at higher *** ...

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