THE BEE VENOM-INDUCED PERSISTENT SPONTANEOUS NOCICEPTION AND HYPERALGESIA IN ELDERLY RATS

作     者：Wei GE~2, Hui-Sheng CHEN~1, Yuan LI~2, Jun CHEN~1 ~1 Department of Anatomy and K.K. Leung Brain Research Centre, ~2 Department of Geriatrics, The Fourth Military Medical University, Xi’an 710032 

出 版 物：《神经解剖学杂志》 (Chinese Journal of Neuroanatomy)

年 卷 期：2001年第17卷第B7期

页      面：107-108页

学科分类：1006[医学-中西医结合] 1002[医学-临床医学] 10[医学] 100602[医学-中西医结合临床] 

主　　题：老龄大白鼠 蜂毒诱发 持续性自发性损伤感受 痛觉过敏 

摘      要：Aim: The bee venom (BV) model in adult rats has been well established. However, the BV-induced multiple aspects of pathological pain have not been studied in elderly (age 22 months) rats. The present study was designed to investigate: (1) response pattern and time course of the BV-indueed persistent spontaneous nociception (PSN) and hyperalgesia in elderly rats; (2) Laminar distribution and time course of the