Cancer immunity and therapy using hyperthermia with immunotherapy, radiotherapy, chemotherapy, and surgery
Cancer immunity and therapy using hyperthermia with immunotherapy,radiotherapy,chemotherapy,and surgery作者机构:Bio-Thera ClinicTokyo 1600022Japan Department of SurgeryInstitute of GastroenterologyTokyo Women’s Medical UniversityTokyo 1628666Japan.
出 版 物:《Journal of Cancer Metastasis and Treatment》 (癌症转移与治疗(英文版))
年 卷 期:2017年第3卷第1期
页 面:218-230页
学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题:Hyperthermia cancer immunity chemosensitizer radiosensitizer combination cancer therapy hyperthermic intraoperative peritoneal chemotherapy
摘 要:Hyperthermia is a type of medical modality for cancer treatment using the biological effect of artificially induced *** though the intrinsic effects of elevated body temperature in cancer tissues are poorly understood,increasing the temperature of the body has been recognized as a popular therapeutic method for tumorous lesions as well as infectious diseases since ancient *** accumulated evidence has shown that hyperthermia amplifies immune responses in the body against cancer while decreasing the immune suppression and immune escape of *** also shows that hyperthermia inhibits the repair of damaged cancer cells after chemotherapy or *** perceptions indicate that hyperthermia has potential for cancer therapy in conjunction with immunotherapy,chemotherapy,radiotherapy,and ***,the anticancer effect of hyperthermia alone has not yet been adequately exploited because deep heating techniques and devices to aggregate heat effects only in cancer tissues are difficult in practical *** review article focuses on the current understanding concerning cancer immunity and involvement of hyperthermia and the innate and adoptive immune *** potential for combination therapy with hyperthermia and chemotherapy,radiotherapy,and surgery is also discussed.