Pharmaceutical evaluation and comparison of different brands of metronidazole available in the local market of Peshawar(Pakistan)
Pharmaceutical evaluation and comparison of different brands of metronidazole available in the local market of Peshawar (Pakistan)作者机构：Department of PharmacySarhad University of Science and Information TechnologyPeshawarKhyber PakhtunkhwaPakistan Health BiotechnologyInstitute of Biotechnology and Genetic EngineeringThe University of AgriculturePeshawarPakistan Department of PharmacyUniversity of SawabiKhyber PakhtunkhwaPakistan
出 版 物：《Journal of Coastal Life Medicine》 (海岸生命医学杂志（英文版）)
年 卷 期：2016年第4卷第8期
页 面：639-644页
学科分类：0202[经济学-应用经济学] 02[经济学] 020205[经济学-产业经济学]
主 题：Metronidazole riability Hardness Weight variation Dissolution Disintegration
摘 要：Objective:To assess the pharmaceutical quality of different brands of metronidazole manufactured,available and prescribed by the doctors of Peshawar,***:Different film-coated metronidazole products manufactured by multinational and national pharmaceutical industries and prescribed by the doctors were collected from Peshawar,Khyber Pakhtunkhwa,*** hysico-chemical properties were assessed,which included friability,hardness,disintegration,dissolution and weight variation tests according to the the United States Pharmacopoeia(USP)***:All the brands showed a average weight of 5.74 g for 13 tablets(products A-M).Product J had the highest weight and products D and E failed the hardness,friability and disintegration time according to USP *** M,K and G,L failed disintegration test and dissolution test,*** variation of all the products proved statistically that they were in accordance with the standards of ***:The study suggested that products A,F,H and J passed all the tests according to the USP standards while the rest of them did not fulfill the standards specification.
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