Crohn's disease with anorectal stenosis successfully treated with vedolizumab

作     者：Darja Urlep Rok Orel 

作者机构：Department of GastroenterologyHepatology and NutritionUniversity Children's Hospital LjubljanaUniversity Medical CenterBohori(c)eva 201000 LjubljanaSlovenia 

出 版 物：《World Journal of Pediatrics》 (世界儿科杂志（英文版）)

年 卷 期：2017年第13卷第4期

页      面：394-395页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Anorectal stenosis Vedolizumab Inflammation 

摘      要：Anorectal stenosis(ARS)is a rare complication of Crohn s disease(CD)and a risk factor for both fecal diversion(FD)and proctectomy,[1,2]especially in patients who failed anti-tumor necrosis factor-α(anti-TNF)therapy)[3,4]Herein,we presented a case of a 17-year-old female diagnosed with CD at age 7,with inflammation located in the small bowel and colon(Paris classification:L3L4b).Due to corticosteroid dependency,infliximab with concomitant azathioprine was introduced at age 9 and discontinued two years after,because of the appearance of a 3 cm tumor-mass,which resembled a lymphoma,in the oral cavity.