An Update on Treatment of Drug-Induced Liver Injury
An Update on Treatment of Drug-Induced Liver Injury作者机构：Department of Faculty and Academic Affairs University of Central Florida College of Medicine Orlando FL USA Digestive Disease Institute Cleveland Clinic Florida Weston FL USA
出 版 物：《Journal of Clinical and Translational Hepatology》 (临床与转化肝病杂志（英文版）)
年 卷 期：2014年第2卷第2期
页 面：74-79页
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题：Drug-induced liver injury Hepatotoxicity Acetaminophen toxicity
摘 要：Drug-induced liver injury (DILI) has been linked to more than 1,000 medications and remains the most common cause of acute liver failure in the United States. Here, we review the most current literature regarding treatment and make recommendations for the management of this relatively common disease. Since treatment of DILI remains largely elusive, recent studies have attempted to define new management strategies for these difficult patients. Early diagnosis and withdrawal of the suspected medication is the mainstay of treatment of DILI. For acetaminophen and Amanita mushroom poisoning, there are specific therapies in use. Finally, there are other possible management mod-alities for DILI, including corticosteroids and ursodeoxycholic acid.
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