Maternal-Fetal Hepatitis E Transmission:Is It Underestimated?

作     者：Maysaa El Sayed Zaki Mohammed Magdy Abd El Razek Hassan Magdy Abd El Razek 

作者机构：Clinical Pathology Mansoura Faculty of Medicine Egypt Mansoura University Hospital Egypt 

出 版 物：《Journal of Clinical and Translational Hepatology》 (临床与转化肝病杂志（英文版）)

年 卷 期：2014年第2卷第2期

页      面：117-123页

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学] 

主　　题：Hepatitis E virus Vertical transmission Prevention 

摘      要：Hepatitis E virus (HEV) is an enterically transmitted virus;and several modes of transmission have been proposed, including blood transfusion, person to person transmission, and transplacental transmission. HEV during pregnancy is asso-ciated with an unfavorable prognosis for mothers and in severe cases can cause acute fulminate hepatitis and death. Transplacental transmission of HEV usually results in unfa-vorable outcomes of pregnancy, mainly fetal loss, preterm labor, and hepatic dysfunction in neonates. In this review, we will summarize the effects of HEV on maternal-fetal health in various clinical situations.