Targeting glioblastoma with oncolytic adenovirus delta 24

作     者：Konstantinos I.Tsamis George A.Alexiou Athanassios P.Kyritsis 

作者机构：Department of NeurologyMedical SchoolUniversity of Ioannina45500 IoanninaGreece 

出 版 物：《Neuroimmunology and Neuroinflammation》 (神经免疫与神经炎症（英文版）)

年 卷 期：2015年第2卷第1期

页      面：1-3页

学科分类：0710[理学-生物学] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100214[医学-肿瘤学] 1009[医学-特种医学] 10[医学] 

主　　题：cytotoxicity delta offering 

摘      要：ONCOLYTIC VIRUSES Oncolytic viruses have been introduced in cancer treatment in the last two decades,offering new opportunities and hopes for ultimate *** studies had also tried to take advantage of the antineoplastic activity of natural viral species,but it was genetic engineering that led to the production of modified viral strains selectively infecting and killing neoplastic cells.[1]The two major characteristics of oncolytic viruses are their tropism for malignant cells and their augmented cytotoxicity.