Flare-up of ulcerative colitis after systemic corticosteroids: A strong case for Strongyloides
Flare-up of ulcerative colitis after systemic corticosteroids: A strong case for Strongyloides作者机构:Department of Gastroenterology Sheba Medical Center and Sackler School of Medicine Tel-Aviv University Pathology Institute Sheba Medical Center and Sackler School of Medicine Tel-Aviv University Department of Medicine E Sheba Medical Center and Sackler School of Medicine Tel-Aviv University
出 版 物:《World Journal of Gastroenterology》 (世界胃肠病学杂志(英文版))
年 卷 期:2008年第14卷第27期
页 面:4413-4415页
核心收录:
学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题:Ulcerative colitis Infection Parasites Eosinophilia Strongyloides
摘 要:Super-imposed infection with intestinal organisms can mimic a flare-up of underlying disease in patients with inflammatory bowel disease (IBD). We report a case of patient with long standing ulcerative colitis (UC), who presented with abdominal pain, diarrhea and low- grade fever after receiving systemic corticosteroids for an unrelated disorder. Despite a negative stool examination, a peripheral eosinophilia reappeared upon tapering down of a corticosteroid dose. Subsequently, duodenal biopsies showed evidence for Strongyloides, presumably acquired 20 years ago when the patient was residing in Brazil. The patient fully recovered following anti-helmintic therapy. This case underscores the importance of considering Strongyloides in the work-up of flaring-up IBD patients, even if a history of residing or traveling to endemic areas is in the distant past.