Facile and Efficient Asymmetric Synthesis of α-Aminoalkylphosphonic Acids

作     者：袁承业 陈谦益 

作者机构：State Key Laboratory of Bio-organic and Natural Products Chemistry Shanghai Institute of Organic Chemistry Chinese Academy of Sciences Shanghai 200032 China 

出 版 物：《Chinese Journal of Chemistry》 (中国化学（英文版）)

年 卷 期：2005年第23卷第12期

页      面：1671-1676页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：Project supported by the National Natural Science Foundation of China (Nos. 20272075 and 20072052) 

主　　题：aminophosphonic acid anilinomethylpyrrolidine asymmetric synthesis 

摘      要：An improved procedure for the asymmetric synthesis of α-aminoalkylphosphonic acids using S-2-anilinomethylpyrrolidine as the chiral auxiliary was described. The chemical transformations involved in this protocol could proceed under mild reaction condition to provide good chemical and enantiomeric yields.