Pathology of Alcoholic Liver Disease

作     者：Romulo Celli Xuchen Zhang 

作者机构：Department of Pathology Yale University School of Medicine New Haven CT USA Pathology and Laboratory Service VA Connecticut Health System and Department of Pathology Yale University School of Medicine West Haven CT USA 

出 版 物：《Journal of Clinical and Translational Hepatology》 (临床与转化肝病杂志（英文版）)

年 卷 期：2014年第2卷第2期

页      面：103-109页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Alcoholic liver disease Steatosis Steatohepatitis Pathology 

摘      要：Alcohol-attributable burden on global health is increasing, and the relationship between population alcohol consumption and liver-related deaths is strong. Longstanding scientific and clinical work has led to a relatively thorough, if not complete, understanding of the effects of alcohol consumption on the liver. Pathologic features of alcoholic liver disease (ALD) are recognized by pathologists and used to assist clinicians in diagnosing and determining severity of disease in patients suspected of ALD. In this review, we discuss the pathologic manifestations of ALD and provide salient points on their pathophysiology. In addition, the benefits and indications of liver biopsy and important differential diagnoses, including features distinguishing these entities, are reviewed.